Facts on Drugs Used in Chemotherapy
Active substance: Vincristine sulfate
Extract from the prescribing information:
"Acute uric acid nephropathy, which may occur after the administration of oncolytic agents, has also been reported with vincristine sulfate."
"Because dose-limiting clinical toxicity is manifested as neurotoxicity, clinical evaluation (eg, history, physical examination) is necessary to detect the need for dosage modification."
The above has been extracted from the Vincasar prescribing information on the Sicor webpages.