Navelbine
Active substance: Vinorelbine
Manufacturer: Pierre Fabre Pharmaceuticals
Extract from the prescribing information:
"Navelbine has been reported to cause severe constipation (e.g., Grade 3-4), paralytic ileus, intestinal obstruction, necrosis, and/or perforation. Some events have been fatal."
"Granulocytopenia is the major dose-limiting toxicity with Navelbine."
The above has been extracted from the Navelbine prescribing information on the Pierre Fabre Pharmaceuticals webpages.