Facts on Drugs Used in Chemotherapy
Active substance: Idarubicin
Extract from the prescribing information:
"As is the case with other anthracyclines the use of IDAMYCIN can cause myocardial toxicity leading to congestive heart failure. Cardiac toxicity is more common in patients who have received prior anthracyclines or who have preexisting cardiac disease."
"IDAMYCIN is a potent bone marrow suppressant. IDAMYCIN should not be given to patients with pre-existing bone marrow suppression induced by previous drug therapy or radiotherapy unless the benefit warrants the risk."
"Formal long-term carcinogenicity studies have not been conducted with idarubicin. Idarubicin and related compounds have been shown to have mutagenic and carcinogenic properties when tested in experimental models"
The above has been extracted from the Idamycin prescribing information on the Pfizer webpages.