Facts on Drugs Used in Chemotherapy
Active substance: Irinotecan
Extract from the prescribing information:
"Irinotecan was clastogenic both in vitro (chromosome aberrations in Chinese hamster ovary cells) and in vivo (micronucleus test in mice)."
"Patients and patients’ caregivers should be informed of the expected toxic effects of CAMPTOSAR, particularly of its gastrointestinal complications, such as nausea, vomiting, abdominal cramping, diarrhea, and infection."
The above has been extracted from the Camptosar prescribing information on the Pfizer webpages.