Chemo Facts

Facts on Drugs Used in Chemotherapy

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Active substance: Mechlorethamine
Manufacturer: Merck & Co., Inc.

Extract from the prescribing information:

"This drug is HIGHLY TOXIC and both powder and solution must be handled and administered with care. Inhalation of dust or vapors and contact with skin or mucous membranes, especially those of the eyes, must be avoided."

"Extravasation of the drug into subcutaneous tissues results in a painful inflammation. The area usually becomes indurated and sloughing may occur."

"Therapy with alkylating agents such as MUSTARGEN may be associated with an increased incidence of a second malignant tumor, especially when such therapy is combined with other antineoplastic agents or radiation therapy."

The above has been extracted from the Mustargen prescribing information on the Merck webpages.