Facts on Drugs Used in Chemotherapy
Active substance: Topotecan
Extract from the prescribing information:
"Bone marrow suppression (primarily neutropenia) is the dose-limiting toxicity of HYCAMTIN."
"Carcinogenicity testing of topotecan has not been performed. Topotecan, however, is known to be genotoxic to mammalian cells and is a probable carcinogen."
The above has been extracted from the Hycamtin prescribing information on the GlaxoSmithKline webpages.