Facts on Drugs Used in Chemotherapy
Active substance: Ifosfamide
Manufacturer: Bristol-Myers Squibb
Extract from the prescribing information:
"Urotoxic side effects, especially hemorrhagic cystitis, as well as CNS toxicities such as confusion and coma have been associated with the use of IFEX."
"Ifosfamide has been shown to be carcinogenic in rats, with female rats showing a significant incidence of leiomyosarcomas and mammary fibroadenomas."
The above has been extracted from the Ifex prescribing information on the Bristol-Myers Squibb webpages.