Facts on Drugs Used in Chemotherapy
Active substance: Cyclophosphamide
Manufacturer: Bristol-Myers Squibb
Extract from the prescribing information:
"Second malignancies have developed in some patients treated with cyclophosphamide used alone or in association with other antineoplastic drugs and/or modalities. Most frequently, they have been urinary bladder, myeloproliferative, or lymphoproliferative malignancies."
"Acute cardiac toxicity has been reported with doses as low as 2.4 g/m2 to as high as 26 g/m2"
The above has been extracted from the Cytoxan prescribing information on the Bristol-Myers Squibb webpages.