Facts on Drugs Used in Chemotherapy
Active substance: Bleomycin sulfate
Manufacturer: Bristol-Myers Squibb
Extract from the prescribing information:
"The carcinogenic potential of BLENOXANE in humans is unknown. A study in F344-type male rats demonstrated an increased incidence of nodular hyperplasia after induced lung carcinogenesis by nitrosamines, followed by treatment with bleomycin."
"Pulmonary toxicities occur in 10% of treated patients. In approximately 1%, the nonspecific pneumonitis induced by BLENOXANE progresses to pulmonary fibrosis, and death."
"It is recommended that BLENOXANE be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents."
The above has been extracted from the Blenoxane prescribing information on the Bristol-Myers Squibb webpages.